Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 14/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 3/20 | 0.39 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | LYN | P07948 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4899241 | 0.88 | CYP1A1 (0.48) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4899309 | 0.83 | SYK (0.40) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| Hydrochloric Acid SCHEMBL27662732 | 0.82 | SYK (0.40) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4899942 | 0.82 | LYN (0.49) | SYKSRCZAP70CDK2LYN | |
| SCHEMBL27682328 | 0.81 | SYK (0.39) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4901619 | 0.81 | EGFR (0.39) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL27682361 | 0.80 | ADORA2A (0.44) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL27682381 | 0.80 | SYK (0.38) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4896690 | 0.79 | SYK (0.49) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4901358 | 0.79 | SLC2A1 (0.49) | SYKCYP1A1CYP1A2CYP1B1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |