Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 7/20 | 0.39 |
| ▸ | SYK | P43405 | 7/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.38 |
| ▸ | SRC | P12931 | 3/20 | 0.38 |
| ▸ | ZAP70 | P43403 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261402 | 0.81 | SYK (0.40) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4897056 | 0.78 | SYK (0.47) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4896690 | 0.76 | SYK (0.49) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4899309 | 0.75 | SYK (0.40) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| Hydrochloric Acid SCHEMBL27662732 | 0.74 | SYK (0.40) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL27682328 | 0.74 | SYK (0.39) | GRM5SYKCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL4899437 | 0.73 | RAB9A (0.49) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL4899942 | 0.73 | LYN (0.49) | SYKSRCZAP70CDK2RAB9A | |
| SCHEMBL4899241 | 0.73 | CYP1A1 (0.48) | SYKCYP1A1CYP1A2CYP1B1SRC | |
| SCHEMBL27682381 | 0.72 | SYK (0.38) | SYKCYP1A1CYP1A2CYP1B1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | ICAGEN, INC. (US) | 2008-05-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080108600-A1 | Polycyclic Pyridines as Potassium Ion Channel Modulators | KCNJ2, KCNH2, KCNQ1 | EGFR 4014/4885GRM5 392/4885SYK 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.