SCHEMBL5261507

SCHEMBL5261507

CC(=O)ON(Cc1ccc(OCCc2nc(-c3ccccc3)oc2C)cc1)S(=O)(=O)N1CCCc2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.53
PPARA Q07869 12/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5263779 0.93 FFAR1 (0.51) PPARGPPARA
SCHEMBL5265445 0.93 PPARG (0.47) PPARGPPARA
SCHEMBL5229106 0.91 PPARG (0.51) PPARGPPARA
SCHEMBL5229830 0.88 PPARG (0.48) PPARGPPARA
SCHEMBL5223343 0.88 PPARA (0.56) PPARGPPARA
SCHEMBL5227389 0.88 PPARG (0.60) PPARGPPARA
SCHEMBL5257668 0.86 KDR (0.51) PPARGPPARA
SCHEMBL5263970 0.85 PPARA (0.49) PPARGPPARA
SCHEMBL5228532 0.85 PPARG (0.50) PPARGPPARA
SCHEMBL5224851 0.85 PPARG (0.53) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778654-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME Crystalgenomics, Inc. (KR) 2007-05-02 EP disclosed
WO-2006006832-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME CRYSTALGENOMICS, INC. (KR) 2006-01-19 WO disclosed