Sugi Predict

Sugi Predict / Compounds / SCHEMBL5229830

SCHEMBL5229830

SCHEMBL5229830

CC(=O)ON(Cc1ccc(OCCc2nc(-c3ccc(C(F)(F)F)cc3)oc2C)cc1)S(=O)(=O)N1CCc2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ PPARG P37231 16/20 0.48
▸ PPARA Q07869 14/20 0.48
▸ TP53 P04637 1/20 0.47
▸ MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5265445 0.96 PPARG (0.47) PPARGPPARATP53MAPT
SCHEMBL5228228 0.94 TP53 (0.47) PPARGPPARATP53MAPT
SCHEMBL5228999 0.93 PPARA (0.50) PPARGPPARA
SCHEMBL5229106 0.92 PPARG (0.51) PPARGPPARATP53MAPT
SCHEMBL5263970 0.89 PPARA (0.49) PPARGPPARA
SCHEMBL5261507 0.88 PPARG (0.53) PPARGPPARA
SCHEMBL5225379 0.88 PPARG (0.54) PPARGPPARATP53MAPT
SCHEMBL5228532 0.86 PPARG (0.50) PPARGPPARATP53MAPT
SCHEMBL5434591 0.86 PPARG (0.48) PPARGPPARATP53MAPT
SCHEMBL5263579 0.86 TP53 (0.53) PPARGPPARATP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1778654-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME Crystalgenomics, Inc. (KR) 2007-05-02 — — EP disclosed
WO-2006006832-A1 SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME CRYSTALGENOMICS, INC. (KR) 2006-01-19 — — WO disclosed