Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.72 |
| ▸ | PTGDR2 | Q9Y5Y4 | 16/20 | 0.65 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113035 | 0.87 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL4628496 | 0.85 | MAPT (0.79) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL14340636 | 0.84 | MAPT (0.77) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL121636 | 0.84 | MAPT (1.00) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL1372961 | 0.83 | MAPT (0.97) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL12830790 | 0.83 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL11110347 | 0.83 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL11106300 | 0.83 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL12463783 | 0.83 | MAPT (0.74) | MAPTPTGDR2PTGDRTDP1TSHR | |
| SCHEMBL2591610 | 0.83 | MAPT (0.97) | MAPTPTGDR2PTGDRTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056752-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | WO | disclosed |