Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537273 | 0.83 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL6518083 | 0.80 | ITGB1 (0.49) | ITGB1ITGA4 | |
| SCHEMBL5260223 | 0.77 | ITGB1 (0.45) | ITGB1ITGA4 | |
| SCHEMBL5264142 | 0.74 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL5262203 | 0.74 | ITGB1 (0.43) | ITGB1ITGA4 | |
| SCHEMBL6514208 | 0.73 | LMNA (0.47) | ITGB1ITGA4 | |
| SCHEMBL5261193 | 0.73 | ITGB1 (0.42) | ITGB1ITGA4 | |
| SCHEMBL6512428 | 0.73 | ITGB1 (0.56) | ITGB1ITGA4 | |
| SCHEMBL5259500 | 0.72 | ITGB1 (0.50) | ITGB1ITGA4 | |
| SCHEMBL5262425 | 0.72 | ITGB1 (0.44) | ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1332132-B1 | ENAMINE DERIVATIVES AS CELL ADHESION MOLECULES | UCB PHARMA SA (BE) | 2007-10-10 | — | — | EP | disclosed |
| US-6780874-B2 | AUTOIMMUNE DISEASE; ANTIINFLAMMATORY AGENTS; ANTIPROLIFERATIVE AGENT | CELLTECH R & D LIMITED (GB) | 2004-08-24 | — | — | US | disclosed |
| US-6610700-B2 | Inhibit binding of integrins to their ligands, use in immune or inflammatory disorders; 3-(4-((2,6-Naphthyridinyl)amino)-phenyl)-2-((2-(1-ethylpropyl)-3-oxo-1 -cyclopentenyl) amino)-propionic acid, for example | CELLTECH R & D LIMITED (GB) | 2003-08-26 | — | — | US | disclosed |