Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 3/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3900553 | 1.00 | DRD2 (0.49) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3901028 | 0.83 | DRD2 (0.48) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3904876 | 0.81 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3898117 | 0.81 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3897829 | 0.81 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3911519 | 0.81 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL1154909 | 0.81 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3900707 | 0.79 | DRD2 (0.54) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3910610 | 0.78 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A | |
| SCHEMBL3899426 | 0.78 | DRD2 (0.46) | DRD2BTKKMT2AL3MBTL1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799639-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | Glenmark Pharmaceuticals S.A. (CH) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006040625-A1 | NOVEL DIPEPTIDYL PEPTIDASE IV INHIBITORS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND PROCESS FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2006-04-20 | — | — | WO | disclosed |