Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 20/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.61 |
| ▸ | HRH1 | P35367 | 1/20 | 0.61 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2984892 | 0.82 | HRH3 (0.64) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL4090418 | 0.81 | HRH3 (0.73) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL12050645 | 0.79 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL4094339 | 0.79 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL3061210 | 0.79 | ALDH1A1 (0.61) | HRH3KCNH2 | |
| SCHEMBL4089489 | 0.78 | HRH3 (0.84) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL12050718 | 0.78 | HRH3 (0.96) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL3581930 | 0.78 | HRH3 (0.89) | HRH3KCNH2HRH1 | |
| SCHEMBL12050716 | 0.77 | HRH3 (0.82) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL4094281 | 0.77 | HRH3 (0.72) | HRH3KCNH2HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | claimed |
| EP-1757594-A1 | QUINAZOLINE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-02-28 | — | — | EP | disclosed |