Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | CCR1 | P32246 | 2/20 | 0.46 |
| ▸ | CCR5 | P51681 | 2/20 | 0.46 |
| ▸ | CCR8 | P51685 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896697 | 0.85 | KMT2A (0.46) | KMT2AHTTMEN1HSD17B10CCR1 | |
| Hydrochloric Acid SCHEMBL4891120 | 0.78 | SLC2A1 (0.62) | KMT2AHTTMEN1CCR1CCR5 | |
| SCHEMBL20919383 | 0.77 | KDM4E (0.68) | KMT2AHTTMEN1HSD17B10CCR1 | |
| SCHEMBL4900002 | 0.74 | GRM5 (0.47) | KMT2AHTTMEN1CCR1CCR5 | |
| SCHEMBL5256919 | 0.73 | SLC2A1 (0.60) | KMT2AHTTMEN1HSD17B10CCR1 | |
| Hydrochloric Acid SCHEMBL4902758 | 0.73 | SMN1; SMN2 (0.61) | KMT2AHTTMEN1HSD17B10CCR1 | |
| SCHEMBL30608756 | 0.73 | KDM4E (0.61) | KMT2AHTTMEN1HSD17B10CCR1 | |
| SCHEMBL19782866 | 0.73 | KDM4E (0.61) | KMT2AHTTMEN1HSD17B10CCR1 | |
| SCHEMBL3139043 | 0.72 | SMN1; SMN2 (0.49) | KMT2AHTTMEN1SMN1; SMN2LMNA | |
| SCHEMBL20919346 | 0.70 | KMT2A (0.57) | KMT2AHTTMEN1CCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1737852-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | Icagen, Inc. (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005100349-A2 | POLYCYCLIC PYRIDINES AS POTASSIUM ION CHANNEL MODULATORS | ICAGEN, INC. (US) | 2005-10-27 | — | — | WO | disclosed |