⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Metacresol SCHEMBL6014969 | 1.00 | ACHE (0.94) | — | |
| Metacresol SCHEMBL2314567 | 0.97 | ACHE (1.00) | — | |
| Metacresol SCHEMBL11437600 | 0.97 | ACHE (1.00) | — | |
| Metacresol SCHEMBL10736 | 0.97 | — | — | |
| Metacresol SCHEMBL9774388 | 0.97 | ACHE (1.00) | — | |
| Metacresol SCHEMBL29352064 | 0.97 | — | — | |
| Metacresol SCHEMBL6118712 | 0.94 | — | — | |
| Metacresol SCHEMBL7070862 | 0.94 | — | — | |
| Metacresol SCHEMBL5533063 | 0.94 | — | — | |
| Metacresol SCHEMBL6234380 | 0.94 | ACHE (0.94) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3578566-B1 | BIOCIDAL PEPTIDE AND PREPARATION BASED THEREON | VERTA RES PRODUCTION COMPANY LTD (RU) | 2023-07-19 | — | — | EP | disclosed |
| EP-3639839-A1 | PEPTIDE WITH ANTIDEPRESSANT ACTIVITY AND THERAPEUTIC EFFECT AGAINST ALZHEIMER'S DISEASE | "Verta Research-Production Company" Ltd (RU) | 2020-04-22 | — | — | EP | disclosed |
| EP-1340744-B1 | Hiv protease inhibitors | AGOURON PHARMA (US) | 2007-05-23 | — | — | EP | disclosed |
| CN-1195737-C | HIV proteinase inhibitor | AGOURON PHARMA (US) | 2005-04-06 | — | — | CN | disclosed |
| EP-0889036-B1 | HIV protease inhibitors | AGOURON PHARMA (US) | 2004-12-29 | — | — | EP | disclosed |
| EP-1212353-A4 | SMALL CYCLIC MIMICS OF BRAIN-DERIVED NEUROTROPHIC FACTOR (BDNF) | UNIV MELBOURNE (AU) | 2004-10-20 | — | — | EP | disclosed |
| US-6693199-B2 | DEPROTECTING CARBAMATE GROUP AND AMIDATING IN PRESENCE OF SUCH AS HYDROXYBENZOTRIAZOLE HYDRATE PROMOTER | AGOURON PHARMACEUTICALS, INC. | 2004-02-17 | — | — | US | disclosed |
| US-20030216569-A1 | Method of making HIV protease inhibitors | DRESSMAN BRUCE A (US) | 2003-11-20 | — | — | US | disclosed |
| EP-1340744-A2 | Hiv protease inhibitors | Agouron Pharmaceuticals, Inc. (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6525215-B2 | As antiviral agents suitable for therapy of patients or hosts infected with the HIV virus, which is known to cause AIDS | AGOURON PHARMACEUTICALS, INC. | 2003-02-25 | — | — | US | disclosed |
| CN-1094399-A | Inhibitors of HIV protease as the treatment AIDS | LILLY CO ELI (US) | 1994-11-02 | — | — | CN | disclosed |
| CN-1092410-A | Inhibitors of HIV protease as the treatment AIDS | LILLY CO ELI (US) | 1994-09-21 | — | — | CN | disclosed |
| EP-0609625-A1 | Inhibitors of HIV protease useful for the treatment of AIDS | ELI LILLY AND COMPANY (US) | 1994-08-10 | — | — | EP | disclosed |
| EP-0604184-A1 | Inhibitors of HIV protease useful for the treatment of aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0604182-A2 | Inhibitors of HIV protease useful for the treatment of Aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0604186-A1 | Inhibitors of HIV protease useful for the treatment of aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0604183-A1 | Inhibitors of HIV protease useful for the treatment of aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| EP-0604185-A1 | Inhibitors of HIV protease useful for the treatment of aids | ELI LILLY AND COMPANY (US) | 1994-06-29 | — | — | EP | disclosed |
| CN-1082035-A | The inhibitors of hiv protease that is used for the treatment of AIDS | LILLY CO ELI (US) | 1994-02-16 | — | — | CN | disclosed |
| EP-0575097-A1 | 2,3-Bis-carboxamidomethyl substituted oxiranes as inhibitors of HIV protease and their use for the treatment of AIDS | ELI LILLY AND COMPANY (US) | 1993-12-22 | — | — | EP | disclosed |