Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.41 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMARCA2 | P51531 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.39 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.38 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.38 |
| ▸ | FYN | P06241 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4842205 | 0.93 | IKBKE (0.41) | IKBKETBK1KDM4ELMNASMARCA2 | |
| SCHEMBL4842844 | 0.76 | IKBKE (0.45) | IKBKETBK1KDM4ELMNAKMT2A | |
| SCHEMBL5260668 | 0.74 | MAP3K11 (0.42) | IKBKETBK1ACHE | |
| SCHEMBL4841712 | 0.74 | KDM4E (0.47) | IKBKETBK1KDM4EACHEALDH1A1 | |
| SCHEMBL4846517 | 0.72 | GAA (0.39) | KDM4ELMNAKMT2AUSP2HPGD | |
| SCHEMBL4838835 | 0.72 | TBK1 (0.64) | IKBKETBK1KDM4EACHEALDH1A1 | |
| SCHEMBL4842559 | 0.72 | POLB (0.45) | KDM4EKMT2AALDH1A1HSD17B10POLB | |
| SCHEMBL4842934 | 0.71 | MEN1 (0.49) | IKBKETBK1KDM4ELMNAKMT2A | |
| SCHEMBL5262429 | 0.71 | MAP3K11 (0.39) | IKBKETBK1ACHE | |
| SCHEMBL5256467 | 0.69 | MAPT (0.41) | KDM4ELMNAKMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1539759-B1 | NOVEL IMIDAZOPYRIDINES AND THEIR USE | ASTRAZENECA AB (SE) | 2007-08-15 | — | — | EP | claimed |