Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 4/20 | 0.43 |
| ▸ | AKT2 | P31751 | 4/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5261963 | 0.89 | AKT1 (0.39) | AKT1AKT2MAPK14 | |
| SCHEMBL5262863 | 0.87 | AKT1 (0.41) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5262639 | 0.85 | AKT1 (0.36) | AKT1AKT2MAPK14 | |
| SCHEMBL5262246 | 0.82 | AKT1 (0.61) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5265191 | 0.82 | AKT1 (0.61) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5264263 | 0.81 | MAPK14 (0.50) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5265058 | 0.81 | AKT1 (0.49) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5261444 | 0.79 | MAPK14 (0.42) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5261530 | 0.79 | AKT1 (0.47) | AKT1AKT2MAPK14MAPK13MAPK12 | |
| SCHEMBL5261876 | 0.78 | ALDH1A1 (0.41) | AKT1AKT2MAPK14MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | S A L V A T LAB SA (ES) | 2007-12-12 | — | — | EP | disclosed |