Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 16/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905854 | 0.80 | HSD11B1 (0.71) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2983487 | 0.77 | HSD11B1 (0.67) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL7980912 | 0.77 | HSD11B1 (0.67) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2994351 | 0.77 | HSD11B1 (0.58) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2989461 | 0.76 | HSD11B1 (0.52) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2990968 | 0.75 | HSD11B1 (0.58) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2747473 | 0.74 | HSD11B1 (1.00) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL2983476 | 0.74 | HSD11B1 (0.61) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| Hydrochloric Acid SCHEMBL2987311 | 0.73 | HSD11B1 (0.52) | HSD11B1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL1417458 | 0.73 | HSD11B1 (0.59) | HSD11B1ALDH1A1NPC1LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1790641-A1 | TRIAZOLE DERIVATIVE OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2007-05-30 | — | — | EP | disclosed |