Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.48 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.48 |
| ▸ | NCF1 | P14598 | 9/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29018525 | 0.81 | ALPL (0.48) | TLR7TLR8ELANEKDM4ENPSR1 | |
| SCHEMBL13200125 | 0.81 | CYP1A2 (0.56) | NCF1ELANEKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL7050208 | 0.80 | BACE1 (0.61) | BACE1NCF1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL832149 | 0.78 | BACE1 (0.58) | BACE1NCF1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL24523711 | 0.78 | ELANE (0.49) | TLR7TLR8ELANEKDM4ENPSR1 | |
| SCHEMBL20809020 | 0.78 | DHODH (0.57) | KDM4ESMN1; SMN2ALDH1A1ADORA3HPGD | |
| SCHEMBL6968709 | 0.77 | BACE1 (0.56) | BACE1NCF1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL832716 | 0.77 | BACE1 (0.56) | BACE1NCF1KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL10330489 | 0.75 | BACE1 (0.59) | BACE1TLR7TLR8NCF1KDM4E | |
| SCHEMBL16836343 | 0.75 | TLR8 (0.58) | BACE1TLR7TLR8NCF1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831219-A2 | A PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE 4-AMINO-1-ISOBUTYL-1H-IMIDAZOÝ4,5-C¨-QUINOLINE (IMIQUIMOD) | USV LIMITED (IN) | 2007-09-12 | — | — | EP | disclosed |
| WO-2006070408-A2 | A PROCESS FOR THE PREPARATION OF SUBSTANTIALLY PURE 4-AMINO-1-ISOBUTYL-1H-IMIDAZO[4,5-C]-QUINOLINE (IMIQUIMOD) | USV LIMITED (IN) | 2006-07-06 | — | — | WO | disclosed |