Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNC | P24863 | 9/20 | 0.64 |
| ▸ | CDK8 | P49336 | 9/20 | 0.64 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | PLAUR | Q03405 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267766 | 0.89 | CCNC (0.61) | CCNCCDK8PIM1HTR2C | |
| SCHEMBL4580362 | 0.87 | CCNC (0.49) | CCNCCDK8SMN1; SMN2 | |
| SCHEMBL4580344 | 0.86 | CCNC (0.50) | CCNCCDK8HTR2C | |
| SCHEMBL15742914 | 0.82 | CCNC (0.72) | CCNCCDK8SMN1; SMN2 | |
| SCHEMBL4580445 | 0.81 | PRKAA2 (0.52) | CCNCCDK8SMN1; SMN2 | |
| SCHEMBL4581298 | 0.80 | ALDH1A1 (0.46) | CCNCCDK8 | |
| SCHEMBL4580301 | 0.80 | CCNC (0.56) | CCNCCDK8PIM1 | |
| SCHEMBL4580434 | 0.80 | CCNC (0.71) | CCNCCDK8 | |
| SCHEMBL4578993 | 0.79 | CCNC (0.54) | CCNCCDK8 | |
| SCHEMBL4580748 | 0.78 | CCNC (0.45) | CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773834-A2 | 2, 8-DISUBSTITUTED NAPHTHYRIDINE DERIVATIVES | Serenex, Inc. (US) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006017672-A2 | 2, 8-DISUBSTITUTED NAPHTHYRIDINE DERIVATIVES | SERENEX INC. (US) | 2006-02-16 | — | — | WO | disclosed |