Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | AKT2 | P31751 | 3/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 5/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5260859 | 0.96 | MAPK14 (0.42) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5263057 | 0.87 | MAPK14 (0.43) | AKT1AKT2MAPK14MAPTMAPK13 | |
| SCHEMBL5261962 | 0.86 | AKT1 (0.43) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5261602 | 0.86 | MAPT (0.45) | AKT1AKT2PTGS1PTGS2MAPT | |
| SCHEMBL5265345 | 0.85 | AKT1 (0.39) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5267924 | 0.84 | MAPK14 (0.41) | AKT1AKT2MAPK14MAPTMAPK13 | |
| SCHEMBL5262188 | 0.82 | MAPT (0.47) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5265447 | 0.80 | AKT1 (0.54) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5263183 | 0.80 | AKT1 (0.49) | AKT1AKT2MAPK14PTGS1PTGS2 | |
| SCHEMBL5263332 | 0.80 | AKT1 (0.38) | AKT1AKT2MAPK14PTGS1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-B1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | S A L V A T LAB SA (ES) | 2007-12-12 | — | — | EP | disclosed |