SCHEMBL526344

SCHEMBL526344

O=C(O)CNCCNCCO

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CAMK2A Q9UQM7 1/20 0.38
CA1 P00915 8/20 0.36
CA2 P00918 8/20 0.36
GPR84 Q9NQS5 1/20 0.35
FFAR1 O14842 1/20 0.35
FFAR4 Q5NUL3 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
LDHA P00338 1/20 0.33
SRR Q9GZT4 1/20 0.33
LMNA P02545 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33
EGLN1 Q9GZT9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10608338 0.97 CAMK2A (0.36) CAMK2ACA1CA2GPR84FFAR1
SCHEMBL203811 0.95
Water SCHEMBL28324777 0.92 CAMK2A (0.39) CAMK2ACA1CA2GPR84FFAR1
Diethanolamine SCHEMBL27742285 0.92 CAMK2A (0.39) CAMK2ACA1CA2GPR84FFAR1
Hydrochloric Acid SCHEMBL7579218 0.92
SCHEMBL27495924 0.92
SCHEMBL3621771 0.92
Phosphine SCHEMBL27836419 0.92
Potassium Ion SCHEMBL27534498 0.90 CAMK2A (0.38) CAMK2ACA1CA2GPR84FFAR1
SCHEMBL1134677 0.89 LMNA (0.41) CA1CA2LDHASRRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-3153798-A None JP disclosed
CN-118255914-A Copolymer having carbosiloxane dendrimer structure, and composition, cosmetic raw material, film-forming agent and cosmetic containing the copolymer 陶氏东丽株式会社 2024-06-28 CN disclosed
CN-117917989-A Use of a reversible metal electrodeposited electrolyte with pH-adjustable, dynamic glass element with high opacity and excellent rest stability, and electrolyte useful therefor 代表内华达大学雷诺分校的内华达高等教育系统董事会 2024-04-23 CN disclosed
CN-106456485-B Liquid oral composition and the method for improving its freezing restoration 狮王株式会社 2019-08-09 CN disclosed
CN-110049756-A ORAL COMPOSITION 狮王株式会社 2019-07-23 CN disclosed
CN-109689016-A Liquid oral composition 狮王株式会社 2019-04-26 CN disclosed
CN-105307623-B Composition for oral cavity containing diamond particles 盛势达(瑞士)有限公司 2018-06-15 CN disclosed
WO-2017189077-A1 HYDROPHILIC SILANES DOW CORNING CORPORATION (US) 2017-11-02 WO disclosed
EP-3229767-A1 CLEANSING COMPOSITION BASED ON A POLYETHYLENE GLYCOL, A POLYETHER ESTER AND A POLYMERIC SUSPENSION AGENT L'Oréal (FR) 2017-10-18 EP disclosed
CN-106821790-A Hair cosmetics composition 朋友株式会社 2017-06-13 CN disclosed
WO-2011078407-A1 COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION AND COSMETIC CONTAINING THE SAME DOW CORNING TORAY CO., LTD. (JP) 2011-06-30 WO disclosed
WO-2011068250-A1 LINEAR AND CYCLIC SILOXANES AND COSMETIC COMPOSITIONS MADE THEREOF DOW CORNING TORAY CO., LTD. (JP) 2011-06-09 WO disclosed
EP-1895979-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE Dow Corning Toray Co., Ltd. (JP) 2008-03-12 EP disclosed
US-20070195309-A1 PHOTOCHROMIC PROBES WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 2007-08-23 US disclosed
WO-2006137576-A1 COSMETICS COMPRISING A MODIFIED ORGANOPOLYSILOXANE DOW CORNING TORAY CO., LTD. (JP) 2006-12-28 WO disclosed
WO-2006112492-A2 ADDITIVES FOR HIGH-CONCENTRATION ANIONIC SURFACTANTS KAO CORPORATION (JP) 2006-10-26 WO disclosed
US-5578642-A ESTERIFICATION OF AZELAIC ACID WITH A FATTY ALCOHOL HENKEL CORPORATION (US) 1996-11-26 US disclosed
EP-0514934-B1 Optically clear hair care compositions containing silicone based microemulsions DOW CORNING (US) 1996-04-10 EP disclosed
JP-H03153798-A LOWLY IRRITANT DETERGENT COMPOSITION KAO CORP 1991-07-01 JP disclosed
US-4121009-A Anti-static fabric softening compositions and processes for drying and softening textiles therewith GAF CORPORATION (US) 1978-10-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070195309-A1 PHOTOCHROMIC PROBES ORAI1, TRPC1, STIM1 CAMK2A 116/4885CA1 97/4885CA2 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.