Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388692 | 0.89 | GPR119 (0.76) | GPR119 | |
| SCHEMBL5260172 | 0.89 | GPR119 (0.65) | GPR119 | |
| SCHEMBL5264940 | 0.88 | GPR119 (0.64) | GPR119 | |
| SCHEMBL5260975 | 0.87 | GPR119 (0.80) | GPR119 | |
| SCHEMBL5263920 | 0.86 | GPR119 (0.62) | GPR119 | |
| SCHEMBL5260768 | 0.86 | GPR119 (0.62) | GPR119 | |
| SCHEMBL5259856 | 0.85 | GPR119 (0.61) | GPR119 | |
| SCHEMBL5262527 | 0.85 | GPR119 (0.61) | GPR119 | |
| SCHEMBL5261927 | 0.85 | GPR119 (0.60) | GPR119 | |
| SCHEMBL5262824 | 0.85 | GPR119 (0.60) | GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1599468-B1 | 1,2,3-TRISUBSTITUTED ARYL AND HETEROARYL DERIVATIVES AS MODULATORS OF METABOLISM AND THE PROPHYLAXIS AND TREATMENT OF DISORDERS RELATED THERETO SUCH AS DIABETES AND HYPERGLYCEMIA | ARENA PHARM INC (US) | 2007-10-03 | — | — | EP | claimed |