Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.45 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | NAMPT | P43490 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | QPCT | Q16769 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2468247 | 0.87 | ALDH1A1 (0.53) | CYP11B1HDAC1HDAC2PTGDR2MAPT | |
| SCHEMBL27682394 | 0.84 | SMN1; SMN2 (0.52) | PTGDR2MAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL5263509 | 0.82 | PTGDR2 (0.58) | CYP11B1HDAC1HDAC2PTGDR2MAPT | |
| SCHEMBL27807801 | 0.82 | MAPT (0.58) | HDAC1HDAC2MAPTSMN1; SMN2NPC1 | |
| SCHEMBL21229063 | 0.80 | NAMPT (0.45) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 | |
| SCHEMBL27717095 | 0.78 | CYP11B1 (0.48) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 | |
| SCHEMBL3065978 | 0.78 | CYP11B1 (0.47) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 | |
| SCHEMBL27856782 | 0.78 | CSNK2A2 (0.40) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 | |
| SCHEMBL4315835 | 0.77 | CYP11B1 (0.65) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 | |
| SCHEMBL18641477 | 0.77 | CYP11B1 (0.41) | CYP11B1HSD17B1HSD17B2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806332-A1 | BENZENE COMPOUND HAVING 2 OR MORE SUBSTITUENTS | Daiichi Sankyo Company, Limited (JP) | 2007-07-11 | — | — | EP | disclosed |