Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3525346 | 0.99 | MAPK14 (0.48) | MAPK14 | |
| Trifluoroacetic Acid SCHEMBL3524114 | 0.94 | MAPK14 (0.46) | MAPK14 | |
| SCHEMBL5269343 | 0.89 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL5263788 | 0.89 | LMNA (0.39) | MAPK14 | |
| SCHEMBL3519143 | 0.89 | MAPK14 (0.46) | MAPK14 | |
| Hydrochloric Acid SCHEMBL3524381 | 0.88 | MAPK14 (0.42) | MAPK14 | |
| SCHEMBL5270363 | 0.87 | MAPK14 (0.47) | MAPK14 | |
| SCHEMBL13602966 | 0.85 | MAPK14 (0.68) | MAPK14 | |
| Hydrochloric Acid SCHEMBL4382509 | 0.84 | MAPK14 (0.67) | MAPK14 | |
| Hydrochloric Acid SCHEMBL29593377 | 0.84 | MAPK14 (0.67) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753731-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | Pharmacia Corporation (US) | 2007-02-21 | — | — | EP | disclosed |
| WO-2004087677-A2 | PYRIMIDIN-4-ONE DERIVATIVES AND THEIR USE AS P38 KINASE MODULATORS | PHARMACIA CORPORATION (US) | 2004-10-14 | — | — | WO | disclosed |