Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | PDE4A | P27815 | 1/20 | 0.68 |
| ▸ | BLVRB | P30043 | 1/20 | 0.68 |
| ▸ | KDR | P35968 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.65 |
| ▸ | APP | P05067 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | RECQL | P46063 | 1/20 | 0.65 |
| ▸ | BLM | P54132 | 1/20 | 0.65 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.62 |
| ▸ | NME4 | O00746 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.62 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.62 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.62 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374390 | 0.87 | MEN1 (0.70) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL1636172 | 0.85 | MEN1 (0.72) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL1636173 | 0.85 | MEN1 (0.72) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL29376111 | 0.85 | MEN1 (0.72) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL24212670 | 0.83 | MEN1 (0.74) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL30452655 | 0.83 | MEN1 (0.74) | MEN1KMT2APDE4ABLVRBKDR | |
| SCHEMBL9689519 | 0.82 | LCK (0.71) | MEN1KMT2APDE4ABLVRBKDR | |
| Olsalazine SCHEMBL29861404 | 0.82 | MEN1 (1.00) | MEN1KMT2APDE4ABLVRBKDR | |
| Olsalazine SCHEMBL25119 | 0.82 | MEN1 (1.00) | MEN1KMT2APDE4ABLVRBKDR | |
| Olsalazine SCHEMBL25118 | 0.82 | MEN1 (1.00) | MEN1KMT2APDE4ABLVRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773767-A2 | SYNTHEIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | Nobex Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006014549-A2 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | NOBEX CORPORATION (US) | 2006-02-09 | — | — | WO | claimed |
| EP-1313697-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | Nobex Corporation (US) | 2003-05-28 | — | — | EP | claimed |
| WO-2002018324-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | claimed |
| EP-1737469-A2 | METHODS AND COMPOSITIONS EMPLOYING 4-AMINOPHENYLACETIC ACID COMPOUNDS | Nobex Corporation (US) | 2007-01-03 | — | — | EP | disclosed |
| WO-2005094448-A2 | METHODS AND COMPOSITIONS EMPLOYING 4-AMINOPHENYLACETIC ACID COMPOUNDS | NOBEX CORPORATION (US) | 2005-10-13 | — | — | WO | disclosed |
| EP-1313697-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | Nobex Corporation (US) | 2003-05-28 | — | — | EP | disclosed |
| WO-2002018324-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |