Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | BLVRB | P30043 | 2/20 | 0.72 |
| ▸ | PDE4A | P27815 | 1/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.72 |
| ▸ | HTT | P42858 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.69 |
| ▸ | BLM | P54132 | 2/20 | 0.69 |
| ▸ | APP | P05067 | 1/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.60 |
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29376111 | 1.00 | MEN1 (0.72) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL1636172 | 1.00 | MEN1 (0.72) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL12153096 | 0.88 | MEN1 (0.68) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL30452655 | 0.86 | MEN1 (0.74) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL24212670 | 0.86 | MEN1 (0.74) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL12040934 | 0.85 | MEN1 (0.59) | MEN1KMT2ABLVRBPDE4AKDR | |
| SCHEMBL5264579 | 0.85 | MEN1 (0.68) | MEN1KMT2ABLVRBPDE4AKDR | |
| Olsalazine SCHEMBL29378994 | 0.85 | MEN1 (1.00) | MEN1KMT2ABLVRBPDE4AKDR | |
| Olsalazine SCHEMBL25119 | 0.85 | MEN1 (1.00) | MEN1KMT2ABLVRBPDE4AKDR | |
| Olsalazine SCHEMBL25118 | 0.85 | MEN1 (1.00) | MEN1KMT2ABLVRBPDE4AKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022182703-A1 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | 9 METERS BIOPHARMA, INC. (US) | 2022-09-01 | — | — | WO | claimed |
| US-20220265684-A1 | COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS | HIGH TRAIL SPECIAL SITUATIONS LLC | 2022-08-25 | — | — | US | claimed |
| US-20220143046-A1 | COMPOSITION AND METHODS FOR RECTAL DELIVERY OF 4-AAPA AND 5-ASA COMPOUNDS | HIGH TRAIL SPECIAL SITUATIONS LLC | 2022-05-12 | — | — | US | claimed |
| WO-2020210809-A1 | COMPOSITION AND METHODS FOR RECTAL DELIVERY OF 4-AAPA AND 5-ASA COMPOUNDS | 9 METERS BIOPHARMA, INC. (US) | 2020-10-15 | — | — | WO | claimed |
| EP-1773767-B1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LTD (IN) | 2016-03-09 | — | — | EP | claimed |
| US-8754197-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2014-06-17 | — | — | US | claimed |
| US-20130096286-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LIMITED (IN) | 2013-04-18 | — | — | US | claimed |
| US-8314214-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2012-11-20 | — | — | US | claimed |
| US-20110201792-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LIMITED (IN) | 2011-08-18 | — | — | US | claimed |
| US-7932366-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2011-04-26 | — | — | US | claimed |
| US-7425578-B2 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | BIOCON LIMITED (IN) | 2008-09-16 | — | — | US | claimed |
| US-20080033153-A1 | Synthesis of Azo Bonded Immunoregulatory Compounds | NOBEX CORPORATION | 2008-02-07 | — | — | US | claimed |
| EP-1773767-A2 | SYNTHEIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | Nobex Corporation (US) | 2007-04-18 | — | — | EP | claimed |
| WO-2006014549-A2 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | NOBEX CORPORATION (US) | 2006-02-09 | — | — | WO | claimed |
| EP-1313697-B1 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORP (US) | 2005-11-30 | — | — | EP | claimed |
| US-6583128-B2 | Phenylazophenylacetic acid derivatives; treating inflammatory bowel disease | NOBEX CORPORATION | 2003-06-24 | — | — | US | claimed |
| EP-1313697-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | Nobex Corporation (US) | 2003-05-28 | — | — | EP | claimed |
| US-20020049186-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION | 2002-04-25 | — | — | US | claimed |
| WO-2002018324-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | claimed |
| US-12414979-B2 | Compositions and methods for treating Sjogren's syndrome | INTERLUDE BIOPHARMA CO. (US) | 2025-09-16 | — | — | US | disclosed |
| WO-2022182703-A1 | COMPOSITIONS AND METHODS FOR TREATING INFLAMMATORY BOWEL DISEASE | 9 METERS BIOPHARMA, INC. (US) | 2022-09-01 | — | — | WO | disclosed |
| US-20220265684-A1 | COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS | HIGH TRAIL SPECIAL SITUATIONS LLC | 2022-08-25 | — | — | US | disclosed |
| US-20220143046-A1 | COMPOSITION AND METHODS FOR RECTAL DELIVERY OF 4-AAPA AND 5-ASA COMPOUNDS | HIGH TRAIL SPECIAL SITUATIONS LLC | 2022-05-12 | — | — | US | disclosed |
| US-20220047668-A1 | COMPOSITIONS AND METHODS FOR TREATING SJOGREN'S SYNDROME | INTERLUDE BIOPHARMA CO. | 2022-02-17 | — | — | US | disclosed |
| WO-2020227341-A1 | COMPOSITIONS AND METHODS FOR TREATING SJOGREN'S SYNDROME | 9 METERS BIOPHARMA, INC. (US) | 2020-11-12 | — | — | WO | disclosed |
| WO-2020210809-A1 | COMPOSITION AND METHODS FOR RECTAL DELIVERY OF 4-AAPA AND 5-ASA COMPOUNDS | 9 METERS BIOPHARMA, INC. (US) | 2020-10-15 | — | — | WO | disclosed |
| EP-1773767-B1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LTD (IN) | 2016-03-09 | — | — | EP | disclosed |
| US-8754197-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2014-06-17 | — | — | US | disclosed |
| US-20130096286-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LIMITED (IN) | 2013-04-18 | — | — | US | disclosed |
| US-8314214-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2012-11-20 | — | — | US | disclosed |
| US-8048924-B2 | Methods and compositions employing 4-aminophenylacetic acid compounds | BIOCON LIMITED (IN) | 2011-11-01 | — | — | US | disclosed |
| US-20110201792-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | BIOCON LIMITED (IN) | 2011-08-18 | — | — | US | disclosed |
| US-7932366-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2011-04-26 | — | — | US | disclosed |
| US-7932366-B2 | Synthesis of azo bonded immunoregulatory compounds | BIOCON LIMITED (IN) | 2011-04-26 | — | — | US | disclosed |
| US-7425578-B2 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | BIOCON LIMITED (IN) | 2008-09-16 | — | — | US | disclosed |
| US-20080033153-A1 | Synthesis of Azo Bonded Immunoregulatory Compounds | NOBEX CORPORATION | 2008-02-07 | — | — | US | disclosed |
| US-20080033153-A1 | Synthesis of Azo Bonded Immunoregulatory Compounds | NOBEX CORPORATION | 2008-02-07 | — | — | US | disclosed |
| US-20070060552-A1 | Methods and compositions employing 4-aminophenylacetic acid compounds | NOBEX CORPORATION | 2007-03-15 | — | — | US | disclosed |
| US-20070004800-A1 | IMMUNOREGULATORY COMPOUNDS AND DERIVATIVES AND METHODS OF TREATING DISEASES THEREWITH | BIOCON LIMITED (IN) | 2007-01-04 | — | — | US | disclosed |
| EP-1737469-A2 | METHODS AND COMPOSITIONS EMPLOYING 4-AMINOPHENYLACETIC ACID COMPOUNDS | Nobex Corporation (US) | 2007-01-03 | — | — | EP | disclosed |
| US-7151095-B2 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION (US) | 2006-12-19 | — | — | US | disclosed |
| US-7119119-B2 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | BIOCON LIMITED (IN) | 2006-10-10 | — | — | US | disclosed |
| EP-1313697-B1 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORP (US) | 2005-11-30 | — | — | EP | disclosed |
| US-20050228051-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION | 2005-10-13 | — | — | US | disclosed |
| WO-2005094448-A2 | METHODS AND COMPOSITIONS EMPLOYING 4-AMINOPHENYLACETIC ACID COMPOUNDS | NOBEX CORPORATION (US) | 2005-10-13 | — | — | WO | disclosed |
| US-6903082-B2 | Methods of treating inflammatory conditions of the gastrointestinal tract using 4-APAA and compositions thereof | NOBEX CORPORATION (US) | 2005-06-07 | — | — | US | disclosed |
| US-20050054728-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION | 2005-03-10 | — | — | US | disclosed |
| US-20030191186-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION | 2003-10-09 | — | — | US | disclosed |
| US-6583128-B2 | Phenylazophenylacetic acid derivatives; treating inflammatory bowel disease | NOBEX CORPORATION | 2003-06-24 | — | — | US | disclosed |
| EP-1313697-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | Nobex Corporation (US) | 2003-05-28 | — | — | EP | disclosed |
| US-20020049186-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | NOBEX CORPORATION | 2002-04-25 | — | — | US | disclosed |
| WO-2002018324-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
| WO-2002018324-A2 | IMMUNOREGULATORY COMPOUNDS, DERIVATIVES THEREOF AND THEIR USE | NOBEX CORPORATION (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (13 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096286-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | C3AR1, HRH4, FCGRT | MEN1 612/4885KMT2A 3091/4885BLVRB 897/4885 |
| US-20220143046-A1 | COMPOSITION AND METHODS FOR RECTAL DELIVERY OF 4-AAPA AND 5-ASA COMPOUNDS | APC, FAP, SI | MEN1 4849/4885KMT2A 873/4885BLVRB 516/4885 |
| US-20070060552-A1 | Methods and compositions employing 4-aminophenylacetic acid compounds | PGA5, AADAT, ALPI | MEN1 4517/4885KMT2A 627/4885BLVRB 3188/4885 |
| US-20030191186-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | MALT1, CCR1, HRH2 | MEN1 2750/4885KMT2A 4092/4885BLVRB 3011/4885 |
| US-20070004800-A1 | IMMUNOREGULATORY COMPOUNDS AND DERIVATIVES AND METHODS OF TREATING DISEASES THEREWITH | HRH2, HRH4, C1R | MEN1 1154/4885KMT2A 4492/4885BLVRB 1345/4885 |
| US-20110201792-A1 | SYNTHESIS OF AZO BONDED IMMUNOREGULATORY COMPOUNDS | CBR1, CBR3, HRH4 | MEN1 1696/4885KMT2A 2509/4885BLVRB 479/4885 |
| US-20050054728-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | HRH2, HRH4, C1R | MEN1 1154/4885KMT2A 4492/4885BLVRB 1345/4885 |
| US-20050228051-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | HRH2, HRH4, C1R | MEN1 1173/4885KMT2A 4497/4885BLVRB 1341/4885 |
| US-20220047668-A1 | COMPOSITIONS AND METHODS FOR TREATING SJOGREN'S SYNDROME | SSB, PDE12, PDE3A | MEN1 3760/4885KMT2A 1191/4885BLVRB 4081/4885 |
| US-20080033153-A1 | Synthesis of Azo Bonded Immunoregulatory Compounds | HRH4, CBR1, ARG1 | MEN1 1541/4885KMT2A 2258/4885BLVRB 475/4885 |
| US-12414979-B2 | Compositions and methods for treating Sjogren's syndrome | SSB, PDE12, PDE3A | MEN1 3760/4885KMT2A 1191/4885BLVRB 4081/4885 |
| US-20220265684-A1 | COMPOSITIONS AND METHODS FOR TREATING ULCERATIVE COLITIS | ALPI, SI, VIP | MEN1 4782/4885KMT2A 424/4885BLVRB 2126/4885 |
| US-20020049186-A1 | Immunoregulatory compounds and derivatives and methods of treating diseases therewith | MALT1, CCR1, HRH2 | MEN1 2750/4885KMT2A 4092/4885BLVRB 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.