Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11511728 | 0.90 | ALDH1A1 (0.46) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL6262534 | 0.89 | ALDH1A1 (0.49) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL11512531 | 0.87 | ALDH1A1 (0.53) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL6257416 | 0.85 | ALDH1A1 (0.45) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL28676524 | 0.81 | ALDH1A1 (0.50) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL5491264 | 0.81 | ALDH1A1 (0.58) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL1149131 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL1875008 | 0.79 | ALDH1A1 (0.56) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL10872347 | 0.78 | ALDH1A1 (0.44) | ALDH1A1GPR35MAPTTDP1MAPK1 | |
| SCHEMBL1091374 | 0.78 | ALDH1A1 (0.54) | ALDH1A1GPR35MAPTTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406577-B1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KGAA (DE) | 2007-10-10 | — | — | EP | disclosed |
| EP-1406577-A1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-04-14 | — | — | EP | disclosed |
| WO-2002100364-A1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-12-19 | — | — | WO | disclosed |