Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.50 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 6/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6416795 | 1.00 | PDE10A (0.56) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL8823975 | 0.98 | PDE10A (0.55) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL15886186 | 0.79 | PDE10A (0.39) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6512953 | 0.78 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29940575 | 0.78 | PDE10A (0.60) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29138695 | 0.77 | PDE10A (0.50) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL244559 | 0.77 | HSP90AA1 (0.59) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL29579675 | 0.77 | PDE10A (0.58) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL294121 | 0.77 | PDE10A (0.58) | PDE10APOLBALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL13093318 | 0.77 | PDE10A (0.63) | PDE10APOLBALDH1A1CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 417 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250146035-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2025-05-08 | — | — | US | claimed |
| US-12188069-B2 | Biocatalyst and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2025-01-07 | — | — | US | claimed |
| CN-111699248-B | Biocatalysts and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds | 密执安大学评议会 | 2024-05-24 | — | — | CN | claimed |
| EP-3746551-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | The Regents Of The University Of Michigan (US) | 2020-12-09 | — | — | EP | claimed |
| US-20200370081-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2020-11-26 | — | — | US | claimed |
| CN-111699248-A | Biocatalysts and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds | 密执安大学评议会 | 2020-09-22 | — | — | CN | claimed |
| WO-2019152679-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2019-08-08 | — | — | WO | claimed |
| CN-106478749-B | 2,3,4- triacetyl -1- (nitro -2- pyridyl group) sulfydryl-α-L- rock algae pyranoside | 宁波大学 | 2019-04-16 | — | — | CN | claimed |
| EP-3262058-A1 | A COMPOUND FOR PREPARING POLYPEPTIDES | Universität Wien (AT) | 2018-01-03 | — | — | EP | claimed |
| CN-106478749-A | 2,3,4 triacetyl 1 (nitro 2 pyridine radicals) sulfydryl alpha L rock algae pyranosides and the synthesis of hydrolyzate | 宁波大学 | 2017-03-08 | — | — | CN | claimed |
| WO-2016135071-A1 | A COMPOUND FOR PREPARING POLYPEPTIDES | Universität Wien (AT) | 2016-09-01 | — | — | WO | claimed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | claimed |
| JP-6228099-A | — | — | None | — | — | JP | disclosed |
| US-12503422-B2 | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor | NEUROBO PHARMACEUTICALS, INC. (US) | 2025-12-23 | — | — | US | disclosed |
| EP-4601685-A1 | MODIFIED LONG PEPTIDES SUITABLE FOR USE IN IMMUNISATION | Isabella Pharma B.V. (NL) | 2025-08-20 | — | — | EP | disclosed |
| US-20250146035-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2025-05-08 | — | — | US | disclosed |
| EP-0089650-B1 | PROCESS FOR PRODUCING ANTIFUNGAL PYRIDAZINONE DERIVATIVES AND CERTAIN NOVEL COMPOUNDS PRODUCED BY SUCH A PROCESS | SANKYO COMPANY LIMITED (JP) | 1986-12-30 | — | — | EP | disclosed |
| US-4603201-A | Process for producing antifungal oyridazinone derivatives | SANKYO COMPANY LIMITED (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0152255-A2 | New renin-inhibitory peptides and their use | SANKYO COMPANY LIMITED (JP) | 1985-08-21 | — | — | EP | disclosed |
| EP-0089650-A1 | Process for producing antifungal pyridazinone derivatives and certain novel compounds produced by such a process | SANKYO COMPANY LIMITED (JP) | 1983-09-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250146035-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | CYP4F3, CYP2E1, CYP1A2 | PDE10A 2837/4885POLB 3859/4885ALDH1A1 395/4885 |
| US-12503422-B2 | Gemcabene, pharmaceutically acceptable salts thereof, compositions thereof and methods of use therefor | NPC1L1, NOTUM, CEL | PDE10A 2356/4885POLB 626/4885ALDH1A1 1952/4885 |
| US-20200370081-A1 | BIOCATALYST AND METHODS FOR SYNTHESIZING MIXED DISULFIDE CONJUGATES OF THIENOPYRIDINE COMPOUNDS | CYP4F3, CYP2E1, CYP1A2 | PDE10A 2837/4885POLB 3859/4885ALDH1A1 395/4885 |
| US-12188069-B2 | Biocatalyst and methods for synthesizing mixed disulfide conjugates of thienopyridine compounds | CYP4F3, CYP2E1, CYP1A2 | PDE10A 2837/4885POLB 3859/4885ALDH1A1 395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.