Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.49 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.47 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | AGER | Q15109 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265077 | 0.82 | TAS2R14 (0.47) | KDM4ETDP1TAS2R14TGFBR1BLM | |
| SCHEMBL30639802 | 0.82 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL30639818 | 0.82 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| Trifluoroacetic Acid SCHEMBL5691131 | 0.80 | KDM4E (0.78) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL270419 | 0.80 | KDM4E (1.00) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL13853227 | 0.80 | TAS2R14 (0.48) | KDM4ETAS2R14ALDH1A1LMNADHODH | |
| SCHEMBL29723448 | 0.78 | KDM4E (0.95) | KDM4ETDP1NAPRTALDH1A1CYP3A4 | |
| SCHEMBL5263715 | 0.74 | CYP1A2 (0.43) | KDM4ETDP1TAS2R14TGFBR1ALDH1A1 | |
| SCHEMBL13853224 | 0.74 | CSNK1D (0.41) | KDM4ETAS2R14DHODHPTGS1PTGS2 | |
| SCHEMBL4197626 | 0.74 | TDP1 (0.61) | KDM4ETDP1NAPRTALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1824828-A2 | PYRIDINE BASED COMPOUNDS USEFUL AS INTERMEDIATES FOR PHARMACEUTICAL OR AGRICULTURAL END-PRODUCTS | Peakdale Molecular Limited (GB) | 2007-08-29 | — | — | EP | claimed |
| WO-2006059103-A2 | PYRIDINE BASED COMPOUNDS USEFUL AS INTERMEDIATES FOR PHARMACEUTICAL OR AGRICULTURAL END-PRODUCTS | PEAKDALE MOLECULAR LIMITED (GB) | 2006-06-08 | — | — | WO | claimed |