SCHEMBL5265182

SCHEMBL5265182

CC[Si](CCCCOCC1CO1)(OC)OC

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.58
ALDH1A1 P00352 4/20 0.57
TDP1 Q9NUW8 1/20 0.57
SMN1; SMN2 Q16637 1/20 0.56
MAPK1 P28482 1/20 0.37
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL230071 0.95 SMN1; SMN2 (0.58) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL767110 0.88 SMN1; SMN2 (0.52) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL3790235 0.88 SMN1; SMN2 (0.50) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL337022 0.86 TSHR (0.61) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL6422835 0.86 SMN1; SMN2 (0.51) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL17373043 0.85 TSHR (0.59) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL11767225 0.84 SMN1; SMN2 (0.61) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL28550914 0.84 SMN1; SMN2 (0.56) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL14840164 0.84 SMN1; SMN2 (0.66) TSHRALDH1A1TDP1SMN1; SMN2MAPK1
SCHEMBL6420038 0.82 SMN1; SMN2 (0.46) TSHRALDH1A1TDP1SMN1; SMN2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5917075-A Hydrolyzable and polymerizable silanes FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG, E.V. (DE) 1999-06-29 US claimed
EP-4269516-A1 COMPOSITION FOR HYBRID POLYMERS HAVING BARRIER FUNCTION Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2023-11-01 EP disclosed
EP-2714653-B1 COMPOUNDS CONTAINING (METH)ACRYLATE GROUPS AND SULFONATE OR SULFATE GROUPS, POLYMERS AND CONDENSATES MADE THEREFROM AND USE OF THE POLYMERS AND CONDENSATES FRAUNHOFER GES FORSCHUNG (DE) 2017-05-03 EP disclosed
US-9353226-B2 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2016-05-31 US disclosed
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2014-03-27 US disclosed
CN-103562318-A Room temperature and humidity thickening thermo-conductive silicon grease composition SHINETSU CHEMICAL CO 2014-02-05 CN disclosed
CN-103378023-A Electric apparatus with excellent exothermic and re-work performance and manufacture method thereof SHINETSU CHEMICAL CO 2013-10-30 CN disclosed
WO-2012163781-A1 COMPOUNDS CONTAINING (METH)ACRYLATE GROUPS AND SULFONATE OR SULFATE GROUPS, POLYMERS AND CONDENSATES MADE THEREFROM AND USE OF THE POLYMERS AND CONDENSATES Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) 2012-12-06 WO disclosed
CN-102585504-A Moisture-thickening heat-conductive silicone grease composition SHINETSU CHEMICAL CO 2012-07-18 CN disclosed
EP-0845489-B1 Use of an agent containing polysiloxanes as antistatic agent for the production of antistatic coatings FRAUNHOFER GES FORSCHUNG (DE) 2007-10-03 EP disclosed
EP-0643752-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1995-03-22 EP disclosed
EP-0643752-A4 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES. PROCTER & GAMBLE (US) 1994-06-03 EP disclosed
WO-1993007230-A1 RESINOUS DENTAL COMPOSITION BASED ON POLYMERISABLE POLYSILOXANES THE PROCTER & GAMBLE COMPANY (US) 1993-04-15 WO disclosed
EP-0525392-A1 Hydrolysable and polymerisable silanes FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) 1993-02-03 EP disclosed
US-4642266-A SCRATCH RESISTANCE AND WEATHERABILITY NIPPON SHEET GLASS CO., LTD. (JP) 1987-02-10 US disclosed
US-RE32272-E EPOXY GROUP-CONTAINING SILANE COMPOUND, POLYHDRIC ALCOHOL, POLYMER AND CURING AGENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-10-28 US disclosed
US-4594379-A Containing an organosilicon compound in photoinitiator blend NIPPON SHEET GLASS CO., LTD. (JP) 1986-06-10 US disclosed
US-4522966-A CURABLE MIXTURE OF GLYCIDYL-CONTAINING ACRYLIC POLYMER, A POLYOXYALKYLENE GLYCOL AND CATALYST NIPPON SHEET GLASS CO., LTD. (JP) 1985-06-11 US disclosed
US-4405679-A ADDITION POLYMER, POLYSILOXANE NIPPON SHEET GLASS CO. LTD. (JP) 1983-09-20 US disclosed
US-4394177-A Coating composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1983-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140088279-A1 Compounds containing (meth)acrylate groups and sulfonate or sulfate groups, polymers and condensates made therefrom and use of the polymers and condensates AS3MT, TST, ALG3 TSHR 3413/4885ALDH1A1 1583/4885TDP1 3767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.