Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | OGT | O15294 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 4/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5866577 | 0.84 | ELANE (0.47) | F2CFDHCAR2OGTELANE | |
| SCHEMBL4509421 | 0.82 | F2 (0.49) | F2CFDOGTELANE | |
| SCHEMBL10771946 | 0.81 | F2 (0.42) | F2CFDHCAR2HCAR3OGT | |
| SCHEMBL10343102 | 0.80 | F2 (0.50) | F2CFDOGTELANE | |
| SCHEMBL6208387 | 0.78 | HCAR2 (0.44) | F2CFDHCAR2HCAR3SORT1 | |
| SCHEMBL19628844 | 0.77 | F2 (0.47) | F2CFDOGTELANE | |
| SCHEMBL5265337 | 0.77 | F2 (0.41) | F2CFDHCAR2HCAR3SORT1 | |
| SCHEMBL4502047 | 0.74 | F2 (0.47) | F2CFDHCAR2OGTELANE | |
| SCHEMBL28766918 | 0.74 | HCAR2 (0.43) | F2CFDHCAR2HCAR3OGT | |
| SCHEMBL15823883 | 0.74 | CYP1A2 (0.52) | F2CFDOGTELANEKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786807-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021340-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-03-02 | — | — | WO | disclosed |