Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CFD | P00746 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 5/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.35 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302703 | 0.84 | DAO (0.46) | F2CFDELANEMCL1 | |
| SCHEMBL18832746 | 0.82 | F2 (0.49) | F2CFDELANEMCL1 | |
| SCHEMBL28329330 | 0.81 | PBRM1 (0.45) | F2CFDELANEHCAR2HCAR3 | |
| SCHEMBL28328122 | 0.80 | MAPT (0.45) | F2CFDELANEMCL1PARP1 | |
| SCHEMBL5265332 | 0.77 | F2 (0.41) | F2CFDELANEHCAR2HCAR3 | |
| SCHEMBL15823884 | 0.74 | FEN1 (0.55) | F2CFDELANEMCL1MAOA | |
| SCHEMBL27899000 | 0.74 | F2 (0.44) | F2CFDMCL1 | |
| SCHEMBL8135133 | 0.73 | ELANE (0.49) | F2CFDELANEMCL1MAOA | |
| SCHEMBL2060660 | 0.72 | F2 (0.52) | F2CFDELANEMCL1 | |
| SCHEMBL21658311 | 0.71 | F2 (0.55) | F2CFDELANEMCL1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786807-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006021340-A1 | HETEROCYCLIC ANTIVIRAL COMPOUNDS | F.HOFFMANN-LA ROCHE AG (CH) | 2006-03-02 | — | — | WO | disclosed |