Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 3/20 | 0.44 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268946 | 1.00 | STS (0.44) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5265399 | 0.91 | STS (0.49) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5264261 | 0.91 | STS (0.49) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5266358 | 0.90 | STS (0.39) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5264536 | 0.90 | STS (0.39) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5265316 | 0.84 | STS (0.60) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5265314 | 0.84 | STS (0.60) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5264144 | 0.84 | STS (0.60) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL5264147 | 0.84 | STS (0.60) | STSABCC1ABCC4CYP1A2CYP3A4 | |
| SCHEMBL7097126 | 0.79 | ABCC1 (0.48) | STSABCC1ABCC4CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1418921-B1 | ANTI-TUMOUR 2-ALKOXYESTRADIOL SULFAMATES | STERIX LTD (GB) | 2007-10-03 | — | — | EP | claimed |
| EP-1418921-B1 | ANTI-TUMOUR 2-ALKOXYESTRADIOL SULFAMATES | STERIX LTD (GB) | 2007-10-03 | — | — | EP | disclosed |