Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 1/20 | 0.48 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.48 |
| ▸ | STS | P08842 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 2/20 | 0.44 |
| ▸ | AR | P10275 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6636478 | 1.00 | ABCC1 (0.48) | ABCC1ABCC4STSKDM4EHSD17B10 | |
| SCHEMBL6633748 | 0.83 | STS (0.44) | ABCC1ABCC4STSKDM4EHSD17B10 | |
| SCHEMBL6633753 | 0.83 | STS (0.44) | ABCC1ABCC4STSKDM4EHSD17B10 | |
| SCHEMBL6871706 | 0.83 | ABCC4 (0.41) | ABCC1ABCC4STSKDM4EHSD17B10 | |
| SCHEMBL5675177 | 0.82 | ESR1 (0.64) | STSHSD17B10ESR1LMNATSHR | |
| SCHEMBL7147482 | 0.82 | ESR1 (0.64) | STSHSD17B10ESR1LMNATSHR | |
| SCHEMBL5265399 | 0.82 | STS (0.49) | ABCC1ABCC4STSHSD17B10ESR1 | |
| SCHEMBL5264261 | 0.82 | STS (0.49) | ABCC1ABCC4STSHSD17B10ESR1 | |
| SCHEMBL3908652 | 0.82 | ABCC1 (0.70) | ABCC1ABCC4STSKDM4EHSD17B10 | |
| SCHEMBL7100301 | 0.82 | ABCC1 (0.47) | ABCC1ABCC4STSKDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775156-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING ESTRA-1,3,5(10)-TRIENE DERIVATIVES | JENAPHARM GMBH (DE) | 2003-09-03 | — | — | EP | claimed |