Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 20/20 | 0.98 |
| ▸ | ADRB1 | P08588 | 20/20 | 0.98 |
| ▸ | ADRB3 | P13945 | 20/20 | 0.98 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | HTR1A | P08908 | 1/20 | 0.79 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.79 |
| ▸ | HTR1B | P28222 | 1/20 | 0.79 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3958888 | 1.00 | ADRB2 (0.98) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4806139 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4806150 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL114610 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4811126 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL185830 | 0.99 | ADRB2 (0.98) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4808416 | 0.99 | ADRB2 (0.98) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4805606 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4809487 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A | |
| SCHEMBL4805616 | 0.99 | ADRB2 (1.00) | ADRB2ADRB1ADRB3CYP3A4HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836452-A2 | APPARATUS AND METHOD FOR MEASURING THE ACCELERATION IMPARTED ON METERED DOSE DELIVERY CONTAINERS | SmithKline Beecham Corporation (US) | 2007-09-26 | — | — | EP | disclosed |
| WO-2006076221-A2 | APPARATUS AND METHOD FOR MEASURING THE ACCELERATION IMPARTED ON METERED DOSE DELIVERY CONTAINERS | SMITHKLINE BEECHAM CORPORATION (US) | 2006-07-20 | — | — | WO | disclosed |