Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33804 | 0.82 | MAPT (0.55) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| Hydrochloric Acid SCHEMBL6259439 | 0.81 | MAPT (0.53) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| SCHEMBL33611 | 0.77 | KDM4E (0.37) | MAPTCDK8ACVR1KDRCSNK1A1 | |
| SCHEMBL6258173 | 0.76 | SMN1; SMN2 (0.57) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| Hydrochloric Acid SCHEMBL7113352 | 0.75 | KDM4E (0.36) | MAPTCDK8ACVR1KDRCSNK1A1 | |
| SCHEMBL11656557 | 0.71 | MAPT (0.58) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| SCHEMBL13860397 | 0.71 | CDK8 (0.50) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| SCHEMBL4214390 | 0.71 | MAPT (0.58) | MAPTCDK8ACVR1CSF1RFGFR1 | |
| SCHEMBL1798141 | 0.70 | MAPT (0.49) | MAPTCDK8ACVR1POLBSMN1; SMN2 | |
| SCHEMBL19926278 | 0.68 | MAPT (0.68) | MAPTCDK8ACVR1CSF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1406577-B1 | NOVEL COUPLER COMPONENTS FOR OXIDATIVE HAIR COLOURING | HENKEL KGAA (DE) | 2007-10-10 | — | — | EP | disclosed |