Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 2/20 | 0.40 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.40 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | GSK3A | P49840 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.39 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL33804 | 0.82 | MAPT (0.55) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| Hydrochloric Acid SCHEMBL6259439 | 0.81 | MAPT (0.53) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| SCHEMBL5265869 | 0.76 | MAPT (0.50) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| SCHEMBL33722 | 0.75 | SMN1; SMN2 (0.52) | SMN1; SMN2HPGDRIPK2 | |
| Hydrochloric Acid SCHEMBL7113251 | 0.74 | SMN1; SMN2 (0.50) | SMN1; SMN2HPGDRIPK2 | |
| SCHEMBL4214390 | 0.71 | MAPT (0.58) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| SCHEMBL13860397 | 0.71 | CDK8 (0.50) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| SCHEMBL19926278 | 0.68 | MAPT (0.68) | SMN1; SMN2HPGDMAPTSRCPOLB | |
| SCHEMBL11656557 | 0.68 | MAPT (0.58) | SMN1; SMN2HPGDMAPTPOLBCDK8 | |
| Benzene SCHEMBL28784168 | 0.67 | ADORA2A (0.46) | MAPTPOLBCDK8CSF1RFGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1233744-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-28 | — | — | EP | claimed |
| WO-2001034104-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | claimed |
| EP-1542647-B1 | Use of hair colouring products comprising 5,6-dihydroxyindoline or a physiologically acceptable salt thereof | HENKEL AG & CO KGAA (DE) | 2014-09-24 | — | — | EP | disclosed |
| EP-1542647-A1 | HAIR COLOURING AGENT COMPRISING INDOLE OR INDOLINE DERIVATIVES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-06-22 | — | — | EP | disclosed |
| WO-2004024109-A1 | HAIR COLOURING AGENT COMPRISING INDOLE OR INDOLINE DERIVATIVES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-25 | — | — | WO | disclosed |
| EP-1233744-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2002-08-28 | — | — | EP | disclosed |
| WO-2001034104-A1 | COLOURING AGENT FOR KERATIN CONTAINING FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-05-17 | — | — | WO | disclosed |