Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 15/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267701 | 0.89 | P2RY12 (0.64) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5266045 | 0.85 | P2RY12 (0.61) | P2RY12MEN1ALDH1A1LMNAHPGD | |
| SCHEMBL5264253 | 0.84 | P2RY12 (0.59) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5268191 | 0.84 | P2RY12 (0.63) | P2RY12MEN1 | |
| SCHEMBL5269075 | 0.83 | P2RY12 (0.54) | P2RY12MEN1HSD17B10ALDH1A1LMNA | |
| SCHEMBL5268059 | 0.83 | P2RY12 (0.62) | P2RY12MEN1 | |
| SCHEMBL5267835 | 0.82 | P2RY12 (0.56) | P2RY12MEN1ALDH1A1KMT2A | |
| SCHEMBL5337425 | 0.80 | P2RY12 (0.46) | P2RY12MEN1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL5337423 | 0.80 | P2RY12 (0.46) | P2RY12MEN1HSD17B10KDM4EALDH1A1 | |
| SCHEMBL5264371 | 0.80 | P2RY12 (0.51) | P2RY12MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |