Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.32 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2115182 | 0.96 | SLC18A3 (0.35) | HRH3L3MBTL3L3MBTL1OPRM1OPRL1 | |
| SCHEMBL2117622 | 0.96 | HRH3 (0.38) | HRH3L3MBTL3L3MBTL1OPRM1OPRL1 | |
| SCHEMBL2115687 | 0.91 | HRH3 (0.35) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL1814912 | 0.84 | SLC18A3 (0.39) | L3MBTL3L3MBTL1OPRM1OPRL1SLC18A3 | |
| SCHEMBL2113705 | 0.83 | HRH3 (0.31) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL5266158 | 0.82 | HRH3 (0.35) | HRH3L3MBTL3L3MBTL1OPRM1ABCB1 | |
| SCHEMBL16387906 | 0.80 | HRH3 (0.41) | HRH3L3MBTL3L3MBTL1ABCB1SLC18A3 | |
| SCHEMBL1828751 | 0.79 | SLC18A3 (0.43) | HRH3L3MBTL3L3MBTL1OPRM1OPRL1 | |
| SCHEMBL2115192 | 0.79 | OPRM1 (0.32) | L3MBTL3L3MBTL1OPRM1OPRL1SLC18A3 | |
| SCHEMBL29750851 | 0.79 | HRH3 (0.36) | HRH3L3MBTL3L3MBTL1ABCB1SLC18A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820797-A1 | SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |