Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 15/20 | 1.00 |
| ▸ | CACNB1 | Q02641 | 15/20 | 1.00 |
| ▸ | CACNA1B | Q00975 | 14/20 | 1.00 |
| ▸ | CACNA1C | Q13936 | 10/20 | 1.00 |
| ▸ | CACNA1G | O43497 | 6/20 | 1.00 |
| ▸ | CACNA1A | O00555 | 2/20 | 0.97 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.84 |
| ▸ | GPX4 | P36969 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4179713 | 1.00 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5268519 | 1.00 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| Z160 SCHEMBL4180792 | 0.92 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5266814 | 0.90 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5265070 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5266285 | 0.88 | CACNA2D1 (0.86) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5270085 | 0.87 | CACNA2D1 (0.77) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5264907 | 0.86 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL5265406 | 0.86 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G | |
| SCHEMBL7665618 | 0.85 | NPC1 (0.78) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1G |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610792-B1 | CALCIUM CHANNEL BLOCKERS COMPRISING TWO BENZHYDRIL MOIETIES | NEUROMED TECH INC (CA) | 2007-10-10 | — | — | EP | claimed |