Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 16/20 | 0.86 |
| ▸ | CACNB1 | Q02641 | 16/20 | 0.86 |
| ▸ | CACNA1B | Q00975 | 14/20 | 0.86 |
| ▸ | CACNA1C | Q13936 | 10/20 | 0.86 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.86 |
| ▸ | CACNA1G | O43497 | 4/20 | 0.78 |
| ▸ | CACNA1A | O00555 | 3/20 | 0.76 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Z160 SCHEMBL4180792 | 0.93 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL5268519 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL4179713 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL5265406 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL5264907 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL5266301 | 0.88 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL8429637 | 0.87 | CACNA2D1 (0.65) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL8427763 | 0.84 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL4352704 | 0.84 | CACNA2D1 (0.78) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H | |
| SCHEMBL5265363 | 0.84 | CACNA2D1 (1.00) | CACNA2D1CACNB1CACNA1BCACNA1CCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1610792-B1 | CALCIUM CHANNEL BLOCKERS COMPRISING TWO BENZHYDRIL MOIETIES | NEUROMED TECH INC (CA) | 2007-10-10 | — | — | EP | claimed |