Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 16/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SMO | Q99835 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5270542 | 1.00 | P2RY12 (0.43) | P2RY12MEN1HTR6KDM4ETMIGD3 | |
| SCHEMBL5264908 | 0.86 | P2RY12 (0.60) | P2RY12MEN1SMO | |
| SCHEMBL5264604 | 0.86 | P2RY12 (0.60) | P2RY12MEN1SMO | |
| SCHEMBL5849347 | 0.83 | MEN1 (0.58) | P2RY12MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7062060 | 0.83 | MEN1 (0.58) | P2RY12MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL5848809 | 0.83 | MEN1 (0.58) | P2RY12MEN1KDM4ESMN1; SMN2 | |
| SCHEMBL4723847 | 0.83 | HTR6 (0.54) | P2RY12MEN1HTR6 | |
| SCHEMBL5851706 | 0.81 | HTR6 (0.43) | P2RY12MEN1HTR6KDM4ESMN1; SMN2 | |
| SCHEMBL5265605 | 0.77 | HTR6 (0.41) | P2RY12MEN1HTR6KDM4ETMIGD3 | |
| Hydrochloric Acid SCHEMBL5265225 | 0.76 | HTR6 (0.41) | P2RY12MEN1HTR6KDM4ETMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1844052-A1 | THIENO[2,3-D]PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | Pharmacia & Upjohn Company LLC (US) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006079916-A1 | THIENO [2,3-D] PYRIMIDINE COMPOUNDS AS INHIBITORS OF ADP-MEDIATED PLATELETS AGGREGATION | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-08-03 | — | — | WO | disclosed |