Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL709839 | 0.78 | MAPT (0.40) | SLC6A4MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL29992857 | 0.76 | ALDH1A1 (0.39) | SLC6A4MAOATYMSHTR2AHTR2C | |
| SCHEMBL29488670 | 0.76 | KDM1A (0.37) | SLC6A4MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL10415734 | 0.76 | SLC6A4 (0.39) | SLC6A4MAOATYMSHTR2AHTR2C | |
| SCHEMBL2111428 | 0.76 | KDM1A (0.37) | SLC6A4MAOAHTR2AHTR2CHTR2B | |
| Bromide SCHEMBL5762669 | 0.76 | MAPT (0.39) | SLC6A4MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL707892 | 0.76 | ALDH1A1 (0.39) | SLC6A4MAOATYMSHTR2AHTR2C | |
| SCHEMBL15793918 | 0.73 | AR (0.44) | HTR2AHTR2C | |
| SCHEMBL30602448 | 0.73 | SLC6A4 (0.37) | SLC6A4MAOAHTR2AHTR2CHTR2B | |
| SCHEMBL30602475 | 0.73 | AR (0.44) | HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781662-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | Pfizer, Inc. (US) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006018725-A1 | INHIBITORS OF HEPATITIS C VIRUS RNA-DEPENDENT RNA POLYMERASE, AND COMPOSITIONS AND TREATMENTS USING THE SAME | PFIZER INC. (US) | 2006-02-23 | — | — | WO | disclosed |