SCHEMBL5266797

SCHEMBL5266797

C=C(CCc1c(F)c(F)c(F)c(F)c1F)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TET2 Q6N021 4/20 0.31
TET3 O43151 1/20 0.31
TET1 Q8NFU7 1/20 0.31
GRIK1 P39086 1/20 0.30
GRIK2 Q13002 1/20 0.30
GRM1 Q13255 1/20 0.30
GRM2 Q14416 1/20 0.30
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30
CNR1 P21554 1/20 0.30
FOLH1 Q04609 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4627065 0.77 TET2 (0.33) TET2TET3TET1GRIK1GRIK2
SCHEMBL2345633 0.77 FFAR1 (0.43) FOLH1
SCHEMBL24386096 0.76
SCHEMBL10890555 0.74 TET2 (0.31) TET2TET3TET1GRIK1GRIK2
SCHEMBL8491907 0.74 CNR1 (0.34) CNR1FOLH1TSHR
SCHEMBL13241364 0.70
SCHEMBL4824446 0.69 FFAR1 (0.54)
SCHEMBL273086 0.69 TET2 (0.46) TET2TET3TET1GRIK1GRIK2
SCHEMBL2922043 0.68 LMNA (0.46) HSD17B10FOLH1TSHR
SCHEMBL18519306 0.68 HTT (0.35) CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1026525-B1 Graded index optical fibre MITSUBISHI RAYON CO (JP) 2007-10-10 EP claimed