Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14205384 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL16004796 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL16004916 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL4654896 | 0.91 | SMN1; SMN2 (0.69) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL143771 | 0.90 | — | — | |
| Butane SCHEMBL150394 | 0.90 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL22418810 | 0.89 | TSHR (0.79) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL20094 | 0.89 | TSHR (0.79) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL16684221 | 0.89 | TSHR (0.79) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 | |
| SCHEMBL17197994 | 0.89 | TSHR (0.79) | SMN1; SMN2ALDH1A1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110234676-B | Low density aerospace compositions and sealants | PRC-迪索托国际公司 | 2022-07-01 | — | — | CN | disclosed |
| CN-107108892-B | Polythioether sealants with extended processing time | PRC-迪索托国际公司 | 2021-05-11 | — | — | CN | disclosed |
| EP-1844767-A2 | Epoxide hydrolase complexes and methods therewith | The Regents of the University of California (US) | 2007-10-17 | — | — | EP | disclosed |
| EP-1154764-B1 | USE OF EPOXIDE HYDROLASE COMPLEXES FOR TREATING HYPERTENSION | UNIV CALIFORNIA (US) | 2007-10-10 | — | — | EP | disclosed |
| US-20060035869-A1 | Inhibitors of epoxide hydrolases for the treatment of hypertension | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA OFFICE OF TECHNOLOGY TRANSFER (US) | 2006-02-16 | — | — | US | disclosed |
| EP-1154764-A4 | EPOXIDE HYDROLASE COMPLEXES AND METHODS THEREWITH | UNIV CALIFORNIA (US) | 2005-02-16 | — | — | EP | disclosed |
| EP-1154764-A1 | EPOXIDE HYDROLASE COMPLEXES AND METHODS THEREWITH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-21 | — | — | EP | disclosed |
| US-6150415-A | TREATING EPOXIDE HYDROLASE TO PURIFY, ISOLATE OR INHIBIT THE ENZYME BY CONTACTING A UREA DERIVATIVE OR OTHER SPECIFIED COMPOUNDS IN FREE OR IMMOBILIZED FORM WITH THE ACTIVE ENZYME TO FORM A COMPLEX WHICH MODIFYS THE ENZYME ACTIVITY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-11-21 | — | — | US | disclosed |
| WO-2000048593-A1 | EPOXIDE HYDROLASE COMPLEXES AND METHODS THEREWITH | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2000-08-24 | — | — | WO | disclosed |
| EP-0012559-B1 | POLYVINYL CHLORIDE - ETHYLENE OXIDE POLYMER BLENDS AND METHODS OF MODIFYING THE IMPACT AND MELT FLOW PROPERTIES OF POLYVINYL CHLORIDE | ROHM AND HAAS COMPANY (US) | 1983-06-22 | — | — | EP | disclosed |
| US-4230827-A | Ethylene oxide polymers as impact modifiers for PVC | ROHM AND HAAS COMPANY (US) | 1980-10-28 | — | — | US | disclosed |
| EP-0012559-A1 | Polyvinyl chloride - ethylene oxide polymer blends and methods of modifying the impact and melt flow properties of polyvinyl chloride | ROHM AND HAAS COMPANY (US) | 1980-06-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060035869-A1 | Inhibitors of epoxide hydrolases for the treatment of hypertension | EPHX1, EPHX2, NCEH1 | SMN1; SMN2 4873/4885ALDH1A1 531/4885TDP1 2783/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.