Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20094 | 1.00 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL22418810 | 1.00 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL17197994 | 1.00 | TSHR (0.79) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL19410605 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL8621977 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| Etoglucid SCHEMBL8442 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL5954227 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL21932618 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL13583289 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 | |
| SCHEMBL5954248 | 0.97 | TSHR (0.75) | TSHRSMN1; SMN2ALDH1A1TDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166993-A1 | POLYAMIDE-BASED WATER-TREATMENT SEPARATION MEMBRANE HAVING EXCELLENT DURABILITY, AND MANUFACTURING METHOD THEREFOR | LG CHEM, LTD. (KR) | 2016-06-16 | — | — | US | disclosed |
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | CARL ZEISS MEDITEC AG (DE) | 2015-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150119356-A1 | Ophthalmic Viscoelastic Device | UACA, ICAM1, VIM | TSHR 4174/4885SMN1; SMN2 4863/4885ALDH1A1 1235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.