Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 4/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.35 |
| ▸ | SLC2A1 | P11166 | 5/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5265408 | 0.89 | KCNH2 (0.40) | KCNH2SLC2A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5315739 | 0.80 | KCNH2 (0.45) | KCNH2SLC2A1SMN1; SMN2 | |
| SCHEMBL5262236 | 0.79 | KCNH2 (0.58) | KCNH2SLC2A1 | |
| SCHEMBL5432954 | 0.75 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL5426370 | 0.75 | — | — | |
| SCHEMBL5264956 | 0.74 | HTR1A (0.42) | SLC6A4 | |
| SCHEMBL5317515 | 0.74 | KCNH2 (0.34) | KCNH2GHSRSLC2A1SMN1; SMN2MEN1 | |
| SCHEMBL5437147 | 0.74 | SLC2A1 (0.32) | KCNH2SLC2A1HTT | |
| SCHEMBL7101571 | 0.71 | KCNH2 (0.66) | KCNH2SLC2A1 | |
| SCHEMBL4468563 | 0.70 | KCNH2 (0.43) | KCNH2SLC2A1PRMT5WDR77MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781650-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft Für Kombinatorische Chemie (DE) | 2007-05-09 | — | — | EP | disclosed |
| WO-2006021448-A1 | NOVEL COMPOUNDS HAVING AN ANTI-BACTERIAL ACTIVITY | Morphochem Aktiengesellschaft für kombinatorische Chemie (DE) | 2006-03-02 | — | — | WO | disclosed |