Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.72 |
| ▸ | NR3C2 | P08235 | 12/20 | 0.72 |
| ▸ | PGR | P06401 | 8/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3578180 | 0.84 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL3574449 | 0.81 | NR3C1 (0.88) | NR3C1NR3C2PGR | |
| SCHEMBL3579037 | 0.80 | NR3C1 (0.88) | NR3C1NR3C2PGR | |
| SCHEMBL3578131 | 0.76 | NR3C1 (1.00) | NR3C1NR3C2PGR | |
| SCHEMBL3573461 | 0.76 | NR3C1 (0.78) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3572117 | 0.74 | NR3C1 (0.78) | NR3C1NR3C2PGR | |
| SCHEMBL3580579 | 0.74 | NR3C1 (0.80) | NR3C1NR3C2PGRMGAM | |
| SCHEMBL3573316 | 0.73 | NR3C1 (0.88) | NR3C1NR3C2PGR | |
| SCHEMBL4407308 | 0.73 | NR3C1 (0.60) | NR3C1NR3C2PGRCYP3A4 | |
| SCHEMBL3571944 | 0.73 | NR3C1 (0.84) | NR3C1NR3C2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836166-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2007-09-26 | — | — | EP | claimed |
| WO-2006071609-A2 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2006-07-06 | — | — | WO | claimed |