Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylene Chloride SCHEMBL27901878 | 0.89 | — | — | |
| SCHEMBL140291 | 0.89 | — | — | |
| SCHEMBL12305761 | 0.89 | — | — | |
| SCHEMBL27747641 | 0.87 | TSHR (0.37) | TSHRTRPA1ALDH1A1 | |
| Bromide SCHEMBL28255766 | 0.85 | — | — | |
| SCHEMBL9584 | 0.84 | — | — | |
| SCHEMBL1331358 | 0.84 | — | — | |
| SCHEMBL27679189 | 0.84 | TSHR (0.54) | TSHRTRPA1ALDH1A1TP53 | |
| SCHEMBL1332028 | 0.84 | — | — | |
| SCHEMBL1331137 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838315-B1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | SANOFI SA (FR) | 2014-03-12 | — | — | EP | disclosed |
| EP-1838315-A1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | sanofi-aventis (FR) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006074813-A1 | SUBSTITUTED 4-PHENYLTETRAHYDROISOQUINOLINES, METHODS FOR PRODUCING THEM, THEIR USE AS DRUG, AND DRUG CONTAINING THEM | SANOFI-AVENTIS (DE) | 2006-07-20 | — | — | WO | disclosed |
| EP-0043465-B1 | REACTIVE DYESTUFFS AND THEIR USE IN DYEING AND PRINTING FIBRE MATERIALS CONTAINING HYDROXYLE GROUPS OR NITROGEN | BAYER AG (DE) | 1984-05-16 | — | — | EP | disclosed |
| EP-0043465-A2 | Reactive dyestuffs and their use in dyeing and printing fibre materials containing hydroxyle groups or nitrogen | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |