Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | MMP9 | P14780 | 2/20 | 0.39 |
| ▸ | MMP8 | P22894 | 2/20 | 0.39 |
| ▸ | MMP12 | P39900 | 2/20 | 0.39 |
| ▸ | MMP14 | P50281 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | NAAA | Q02083 | 3/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268750 | 1.00 | PTGS2 (0.42) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL6255401 | 0.96 | PTGS2 (0.42) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5267215 | 0.94 | PTGS2 (0.43) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5266056 | 0.93 | PTGS2 (0.41) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5266959 | 0.93 | PTGS2 (0.41) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5264764 | 0.91 | PTGS2 (0.41) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL6252730 | 0.91 | PTGS2 (0.41) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5267743 | 0.90 | PTGS2 (0.40) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5266960 | 0.90 | PTGS2 (0.40) | PTGS2MMP2MMP9MMP8MMP12 | |
| SCHEMBL5271286 | 0.89 | PTGS2 (0.40) | PTGS2MMP2MMP9MMP8MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1742608-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϝ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | Galderma Research & Development, S.N.C. (FR) | 2007-01-17 | — | — | EP | disclosed |
| WO-2005108352-A1 | NOVEL BIAROMATIC COMPOUNDS WHICH ACTIVATE PPARϜ-TYPE RECEPTORS, THEIR PROCESS OF PREPARATION AND THEIR USE IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RESEARCH & DEVELOPMENT, S.N.C. (FR) | 2005-11-17 | — | — | WO | disclosed |