Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VEGFA | P15692 | 12/20 | 0.69 |
| ▸ | EGLN1 | Q9GZT9 | 12/20 | 0.69 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.44 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272075 | 0.99 | VEGFA (0.70) | VEGFAEGLN1RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL271963 | 0.90 | EGLN1 (0.85) | VEGFAEGLN1HRH3SMN1; SMN2 | |
| SCHEMBL277668 | 0.90 | EGLN1 (0.85) | VEGFAEGLN1HRH3SMN1; SMN2 | |
| SCHEMBL273696 | 0.90 | EGLN1 (0.85) | VEGFAEGLN1HRH3SMN1; SMN2 | |
| SCHEMBL273037 | 0.89 | EGLN1 (0.87) | VEGFAEGLN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12598832 | 0.85 | VEGFA (0.73) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL17340662 | 0.84 | VEGFA (0.49) | VEGFAEGLN1RECQLL3MBTL1ALDH1A1 | |
| SCHEMBL278202 | 0.82 | VEGFA (1.00) | VEGFAEGLN1ALDH1A1SMN1; SMN2 | |
| SCHEMBL278211 | 0.82 | VEGFA (0.75) | VEGFAEGLN1ALDH1A1 | |
| SCHEMBL277620 | 0.80 | EGLN1 (0.71) | VEGFAEGLN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558579-B1 | N-ALKYL-4-METHYLENEAMINO-3-HYDROXY-2-PYRIDONES AS ANTIMICROBIALS | PROCTER & GAMBLE (US) | 2007-09-12 | — | — | EP | claimed |