Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 7/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | HRH1 | P35367 | 2/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5268919 | 0.93 | MAPT (0.39) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL5269559 | 0.83 | MAPT (0.36) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL4878558 | 0.82 | MAPT (0.56) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL4883990 | 0.81 | MAPT (0.39) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL2781332 | 0.78 | KMT2A (0.39) | MAPTKMT2AALDH1A1MEN1LMNA | |
| SCHEMBL4878565 | 0.75 | MAPT (0.60) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL5270882 | 0.74 | L3MBTL1 (0.34) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL4885915 | 0.73 | MAPT (0.61) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 | |
| SCHEMBL5269800 | 0.73 | CHRM2 (0.37) | MAPTKMT2AALDH1A1MEN1NPSR1 | |
| SCHEMBL4881541 | 0.73 | MAPT (0.43) | SMN1; SMN2MAPTKMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1838659-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK Pharmaceuticals D.D. (SI) | 2007-10-03 | — | — | EP | disclosed |
| WO-2006066931-A1 | PROCESS FOR PREPARATION OF 3-(2-HYDROXY-5-METHYLPHENYL)-N,N-DIISOPROPYL-3PHENYLPROPYLAMINE | LEK PHARMACEUTICALS D.D. (SI) | 2006-06-29 | — | — | WO | disclosed |