Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 6/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2118658 | 0.90 | NPC1 (0.39) | HRH1NPC1 | |
| SCHEMBL2116796 | 0.90 | NPC1 (0.43) | HRH1NPC1MEN1KMT2ALMNA | |
| SCHEMBL2886464 | 0.90 | NPC1 (0.35) | ESR1HRH1NPC1LIPG | |
| SCHEMBL5267861 | 0.85 | NPC1 (0.33) | ESR1NPC1CHRM2CHRM3 | |
| SCHEMBL2116173 | 0.81 | HRH1 (0.39) | HRH1MEN1KMT2ALMNAPOLB | |
| SCHEMBL19616664 | 0.77 | GRIN1 (0.33) | HRH1MEN1KMT2ALMNAPOLB | |
| SCHEMBL2114234 | 0.77 | GRIN1 (0.33) | HRH1MEN1KMT2ALMNAPOLB | |
| SCHEMBL18159722 | 0.77 | GRIN1 (0.33) | HRH1MEN1KMT2ALMNAPOLB | |
| SCHEMBL20755363 | 0.77 | CHRM2 (0.34) | ESR1MEN1KMT2ACHRM2CHRM3 | |
| SCHEMBL2118654 | 0.76 | NPC1 (0.38) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1820797-A1 | SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-08-22 | — | — | EP | disclosed |