Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HRH1 | P35367 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267864 | 0.90 | ESR1 (0.33) | NPC1LIPGESR1HRH1 | |
| SCHEMBL5267861 | 0.81 | NPC1 (0.33) | NPC1ESR1 | |
| SCHEMBL2118658 | 0.80 | NPC1 (0.39) | NPC1HRH1 | |
| SCHEMBL2116796 | 0.79 | NPC1 (0.43) | NPC1HRH1 | |
| SCHEMBL15685469 | 0.76 | SLC18A3 (0.37) | SLC18A3MAPK1 | |
| SCHEMBL15685468 | 0.76 | SLC18A3 (0.37) | SLC18A3MAPK1 | |
| SCHEMBL6043379 | 0.76 | SLC18A3 (0.37) | SLC18A3MAPK1 | |
| Hydrochloric Acid SCHEMBL25364283 | 0.74 | SLC18A3 (0.36) | SLC18A3MAPK1 | |
| SCHEMBL15833659 | 0.73 | LIPG (0.35) | NPC1LIPGESR1 | |
| SCHEMBL2118654 | 0.72 | NPC1 (0.38) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7732456-B2 | Pyridone derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-08 | — | — | US | disclosed |
| US-20070208046-A1 | Pyridone derivative | MSD K.K. (JP) | 2007-09-06 | — | — | US | disclosed |
| EP-1741703-A1 | PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2007-01-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208046-A1 | Pyridone derivative | CHRM1, XDH, MTR | NPC1 4658/4885SLC18A3 3595/4885LIPG 4860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.